A quantitative recipe for engineering protein polymer nanoparticles

Protein-polymer hybrid nanoparticles for drug delivery.

Amphiphilic bovine serum albumin-poly(methyl methacrylate) conjugate forms nanoparticles with the uniform size of ~100 nm by self-assembling. Loaded with the hydrophobic anti-tumor drug camptothecin, the nanoparticle efficiently delivers drugs into cancer cells, and thus inhibits ~79% of tumor growth in animals compared with free drug.

Orange and Sunlight: A Recipe for Blisters

NIRCam Systems Engineering: The Recipe

NIRCam is a highly sensitive, multi-spectral, high-resolution, cryogenic, compact, light-weight, and rugged near infrared camera on the James Webb Space Telescope. The successful development of NIRCam is aided by good system engineering practice. This is a discussion of important elements of NIRCam System Engineering with some lighthearted contrast to a more common activity.

Conjugated polymer nanoparticles for biochemical protein kinase assay.

Sensitive and reliable monitoring of kinase activity was reported by using highly efficient fluorescence resonance energy transfer of conjugated polymer nanoparticles (CPNs) to a rhodamine labelled peptide substrate.

Conjugated Polymer Nanoparticles for Bioimaging

During the last decade, conjugated polymers have emerged as an interesting class of fluorescence imaging probes since they generally show high fluorescence brightness, high photostability, fast emission rates, non-blinking behavior and low cytotoxicity. The main concern related to most conjugated polymers is their lack of hydrophilicity and thereby poor bio-availability. This can, however, be o...